San Sebastian ranks as one of Florida's premium wineries, and remains a pioneer in the development of premium, sparkling and dessert wines from Muscadine grapes. Vinifera wines are also produced to include Chardonnay, Pinot Grigio, Petite Sirah and Cabernet Sauvignon and are marketed along with blended and sparkling wines from native Muscadine grapes. Port and Cream Sherry dessert wines are also produced by and sold under the San Sebastian brand. Together, these labels have won many awards for excellence in winemaking, over 744 so far with more to come each season.

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